Palliative Care & Treatment for Kidney Failure - A General Guide

1. Kidney Failure in Singapore

According to the National Kidney Foundation (NKF), 5.5 new patients get diagnosed with kidney failure daily in Singapore. The country is ranked fourth in the world for prevalence of kidney failures, and first for diabetes-induced kidney failures, both of which are worrying ‘records’. The incidents are significantly more common among older adults. Among newly diagnosed kidney failure cases, 80% of cases are aged 50 and above, according to a study published by NUH. 

Kidney failure is a serious condition but it is possible to manage it so that patients can still lead meaningful lives. In this article, we will discuss treatment and care for kidney failure, with a focus on palliative care for kidney failure - an important part in the therapeutic approach to help kidney failure patients maintain their quality of life.

2. What is Kidney Failure?

Kidney Failure refers to the most advanced stage in the 5 stages of Chronic Kidney Disease (CKD), in which the kidneys only function at 15% of their capacity or less. Kidney is medically referred to as ‘renal’. Kidney failure is therefore also called renal failure, or End-Stage Renal Disease (ESRD). 

Most kidney failure cases are chronic, often progressing from early stage chronic kidney disease, which in turn is caused by various diseases such as diabetes, high blood pressure, glomerulonephritis (inflammation of kidney tissues), or polycystic kidney disease. To learn more about causes of common kidney diseases in Singapore, their causes and treatment, and how they can cause kidney failure, read our blog article here.

The two main treatments for ESRD include dialysis (more details below) and kidney transplantation. Kidney transplantation is a surgical procedure that involves the graft of a new kidney from a healthy individual who can be a family member (genetically related kidney transplantation) or non-related person (genetically non-related kidney transplantation).

3. Dialysis Treatment for Kidney Failure

Dialysis is one of the main treatments for kidney failure. It is the process of using an ‘alternative kidney’ to perform the part of kidney functions that the failing kidneys are unable to do, including removing waste and toxins from blood, regulating electrolytes and blood pressure, and maintaining homeostasis. There are two main types of dialysis - hemodialysis and peritoneal dialysis.

3.1. Hemodialysis

In hemodialysis, the ‘alternative kidney’ is an external artificial kidney machine. Patients usually have to go to a dialysis centre at a clinic or hospital to use the machine 3 to 4 times a week. Each session lasts about 4 hours. Blood from the body is passed through the machine, filtered and then transferred back to the body. 

Kidney failure patients under hemodialysis have to follow a strict diet regime. Fluid intake is usually restricted to 1 to 1.5 litres per day, instead of the usual recommended 2 litres per day. Minerals intake such as salt, potassium and calcium also need to be watched carefully. These restrictions help to avoid the build-up of fluid and minerals in the body between dialysis sessions, which can have severe consequences such as heart and lung problems or bone disorders. 

Hemodialysis is the main form of dialysis that kidney failure patients receive. Apart from regular trips to dialysis centres and dietary requirements, patients on hemodialysis can live their life ‘freely’ the rest of the time. 

3.2. Peritoneal dialysis

In peritoneal dialysis, the filter of the ‘alternative kidney’ is another part of the body called the peritoneum, which is the membrane lining the walls of the abdomen. A catheter is permanently inserted in the abdomen region, allowing for the injection of an external fluid called dialysate, or dialysis fluid, into the peritoneal cavity. The peritoneum and dialysate fluid filter and draw out waste, toxins and excess fluid from the blood. 

Different from hemodialysis, the filtering process happens inside the body and blood is not transferred out of the body. After a few hours when dialysis fluid is filled up with waste products, it is transferred to a drainage bag located outside the body. The process then needs to be repeated again, with the use of new dialysate (dialysis fluid).

At night, peritoneal dialysis can be automated with the help of a machine, allowing patients to sleep through the night. Compared to hemodialysis, patients on peritoneal dialysis usually have less diet restrictions, due to more frequent clearing of unwanted products from the body. They also do not need to visit a clinic or hospital for the procedure. It can be safely carried out at home, and less costly.

However, the number of times peritoneal dialysis procedure needs to be performed a day means that patients cannot be away from the dialysis equipment for long. Some patients may also be sensitive to a catheter or find it inconvenient, making peritoneal dialysis unsuitable for them. 

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4. Why is Palliative Care Necessary for Kidney Failure Patients?

When kidney failure or ESRD occurs, most of the kidney’s function is lost. Dialysis helps replace kidney functions to a large extent. However, symptoms and complications can manifest between treatment sessions or over time if the condition is progressive. In some cases, patients may not opt for dialysis, for various personal or medical reasons, and may experience a wide range of physical symptoms and thereby, an impaired quality of life.

A comparison study revealed that symptom burden of kidney failure in fact is similar to those with advanced cancer. About half of kidney failure patients or more experience fatigue, itchiness, breathlessness, constipation, loss of appetite and pain, according to statistics. Other medical complications from kidney failure include hypertension, hyperkalemia (accumulation of potassium in the blood), edema (fluid retention), hypocalcemia (reduced blood calcium levels), metabolic acidosis (acidic blood PH), anemia (underproduction of red blood cells), and decreased libido. 

Well-being and psychological symptoms ranging from poor quality of sleep to anxiety and depression are also widely reported. Faced with the prospect of a lifetime dependency on dialysis, financial burden and changing role in family and at work, many patients as well as patients’ families find it hard to cope without social, psychological and spiritual support. In short, the need for symptom control among kidney failure patients is large and diverse, and often cannot be addressed adequately by curative treatment. Palliative care is designed to fill in the gap.

Palliative care is the specialised care with the aim of improving the quality of life for both patients and their family. A palliative care team for kidney failure often consists of a palliative doctor or palliative specialist, kidney doctor, nurse, caregiver, counsellor, even social workers or volunteers. They work together to help kidney failure patients and their families navigate the unfamiliar journey of treating and caring for kidney failure, help them make critical decisions in line with their care goals, manage physical and psychological pain and other symptoms, and in general improve their quality of life. 

In the following part of the article, we discuss 5 ways palliative care can help kidney failure patients and their families. If you need an overview of palliative care in Singapore, check out our article here.

5. Aspects of Palliative Care in Kidney Failure Care

Patients with kidney failure may suffer from a wide range of physical and mental distress, as a direct result of the condition, or of the strict diet and treatment schedule they have to follow. Their family members and caregivers who they depend on can also be under enormous pressure to provide comfort and care to their loved one around the clock. Between trips to the doctor and clinic, both the patients and families need a lot of help. Below are a number of ways that palliative care can support kidney failure patients and their families.

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5.1. Manage pain and other symptoms and complications

Since palliative care focuses on reducing the patient’s suffering, management of pain is a cornerstone of this practice. Over 70% of kidney failure patients are reported to experience pain, often related to bone deterioration as a result of an imbalance in the levels of calcium and other minerals. Having access to a palliative care plan, the patient can expect that their pain will be addressed with appropriate medication and therapy. Other symptoms such as fatigue, breathlessness 

Aside from pain, the palliative care team takes care of other complications and conditions related to kidney failure as situations require, including heart disease, high blood pressure, irregular blood sugar, low urine output, urinary tract infections, etc. 

5.2. Explain the disease process and manage expectations

When you meet with your palliative team, they will explain to you the disease process, how it develops over time, and the steps you can take to manage your condition. They will also help you and your family understand the expectations behind the treatments you are taking and the timeline of symptom improvement. This is vital since setting the bar too high is often the reason patients get depressed and anxious.

5.3. Help the patient and family make critical decisions

Your palliative care team will be part of critical decisions related to treatment options. For instance, when your kidney doctor recommends hemodialysis, or peritoneal dialysis, or a kidney transplant, the palliative care team will help you understand the goals, benefits, and side effects of each treatment, which will make the decision much easier for you.

As another example, a kidney patient may not be fit for dialysis due to comorbidity. However, the patient's health condition is likely to worsen without the supporting ‘artificial kidney’. In this scenario, the palliative care team will be able to help the understand the options available and decide how to best manage the disease and possible complications without the curative dialysis treatment.

Regardless of the patient's decision, once it is made, the palliative care team will be there to support the patient before, during, and after the procedure. For instance, if you decide to get a kidney transplant, you will likely require extensive care after the procedure. Going through this by yourself can be daunting for you and your family, which is where palliative care experts come in handy.

5.4. Help you cope with the mental burden

While people mainly associate kidney failure with physical symptoms, the mental burden of these conditions is just as heavy. According to one study, patients with chronic, incurable illnesses are significantly more likely to develop psychiatric disorders, such as major depression and generalised anxiety disorder.

Fortunately, this is one aspect of care your palliative team will take into account when providing palliative care to you. You will receive emotional support and spiritual guidance to help you get through these difficult times, from the palliative core team as well as the extended team, consisting of counsellors, therapists, social workers, etc. Some of the therapies that may help with this process include massages, relaxation techniques, and talk therapy.

5.5. Help you do advance care planning (ACP)

Advance care planning (or ACP) is the process of planning for future care requirements when the person is still healthy. Kidney failure, though treatable, may have serious and sudden complications. Having an advanced care plan handy, the care team and family will be able to react quickly according to the patient's care wishes and preferences that are planned out earlier during the ACP process. 

The role of the palliative care team is to help kidney failure patients and their families navigate possible care scenarios and make choices in advance, including end-of-life care decisions. The ultimate purpose is not to plan for the worst, but to ensure the patient receives the best treatment and care according to their needs, wants and goals. To find out more ACP, its benefits and steps to get started, read our guide here. To better understand how palliative can provide compassionate support to patients and families navigating the final chapters for a loved one, read our article here

6. Improve your Well-Being with Palliative Care

We hope that this article explains the role and aspects of curative treatment and palliative care for kidney failure patients. Kidney failure, or end stage renal kidney disease, is the last stage of chronic kidney disease, signifying a major loss of kidney function. Though treatable with treatments such as dialysis and kidney transplant, kidney failure patients often experience physical symptoms such as pain, fatigue, breathlessness as well as psychological symptoms, leading to a compromised quality of life. Thankfully, palliative care offers the benefits of relieving pain and easing up other challenges for the patients and improving their quality of life, as well as that of their families. 

To learn more about palliative care for the specific circumstance of yourself or your loved one, check out our Ninkatec palliative care plans, and call or chat with our care team for a personal consultation. With Ninkatec’s 24/7 monitoring technology and palliative care service provided in the comfort of your home, kidney failure patients and families can be assured that Ninkatec care team is always with you every step of the way. 



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